α V β 6 Integrin: An Intriguing Target for COVID‐19 and Related Diseases
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چکیده
منابع مشابه
Expression of Integrin Α V Β 6 and Tgf - Β in Scar - Free Vs . Scar - Forming Wound Healing
Background: Raman spectroscopy is a non-invasive optical technique, which has the capability in determining the molecular structure and conformation of biochemical constitutes. Recently we developed a rapid real-time Raman spectrometer system, paving the way for clinical application of Raman spectroscopy. Hypothesis: The morphological structure and the bio-molecular constitutes have been altere...
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A substantial and persuasive body of data now exists that supports the view that integrin alpha V beta 3 plays a critical part in activated macrophage dependent inflammation, osteoclast development, migration, and bone resorption, and inflammatory angiogenesis. All of these processes play an important part in the pathogenesis of rheumatoid arthritis (RA) and related arthropathies. Animal arthri...
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BACKGROUND/AIMS Laminar shear stress is an important stimulus in the endothelium-dependent control of vascular tone and of vascular remodeling processes. Based on previous studies demonstrating integrin-mediated release of fibroblast growth factor 2 (FGF-2), we investigated whether shear stress-induced integrin activation requires the involvement of an extracellular protease. METHODS Cultured...
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15 صفحه اولα 5 β 1 integrin mediates strong tissue cohesion
Cell-cell and cell-extracellular matrix (ECM) interactions are fundamental regulators of both normal and abnormal biological processes including morphogenesis (Fujimori et al. The roles of cadherins and integrins in these processes are well defined but have traditionally been considered as having two distinct and opposing functions. Cadherins regulate strong cell-cell cohesion, whereas integrin...
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ژورنال
عنوان ژورنال: ChemBioChem
سال: 2021
ISSN: 1439-4227,1439-7633
DOI: 10.1002/cbic.202100209